The role of intravenous tranexamic acid for blood loss in total hip arthroplasty secondary to femoral neck fracture

Aim: The aim of the study was to compare efficacy intravenous (IV) administration tranexamic acid (TXA) in terms bleeding volume, allogeneic blood transfusion (ABT) requirement, and complications total hip arthroplasty (THA) secondary osteoporotic femoral neck fracture (FNF).
 Material Method: A 165 patients who underwent THA on background FNF our clinic were included study. Patients' demographic data, preoperative postoperative parameters, amount loss calculated according Nadler formula, ABT, at 90-day follow-up recorded. divided into two groups those received 15mg/kg preoperatively 10mg/kg IV TXA end operation (TXA group-89 patients) did not receive (Control group-76 compared.
 Results: formula significantly less group (1659,68±320,86ml) compared with Control (1774,43±365,24ml) (p=0.033). need for ABT 42.86% 57.14% control group, this difference statistically significant (p=0.008).
 Conclusion: In basis FNF, 2 doses reduced ABT. We suggest that can be safely performed, especially patient reduce therefore by increasing any thromboembolic complications.